EFFECT OF PIPERONYL BUTOXIDE ON THE BIOLOGICAL ACTIVITY OF SOME SYNTHETIC PYRETHROID INSECTICIDES USED IN PUBLIC HEALTH IN TURKEY

Abstract

In this study, it was aimed to show the effect of piperonyl butoxide (PBO) on the biological activities of cypermethrin, deltamethrin and permethrin and to determine whether there are differences in respect to the effects among insecticides used on laboratory (WHO) and field (Ankara) populations of houseflies. Three groups were included as cypermethrin, deltamethrin, and permethrin alone and combinations with PBO synergist compound at 1:1 and 1:3 ratio. The biological effects of these active ingredients on 4-6 days old houseflies were determined by a derivation of the standard permanent surface method proposed by WHO. During the experimental process, knockdown and mortality percentages, knockdown time and knockdown resistance coefficients were determined. Mortality and knockdown percentages were found to be very lower in Ankara housefly populations than WHO housefly populations using insecticides alone. PBO highly increased the knockdown and mortality percentages of insecticides on Ankara housefly populations and as well as decreased knockdown times. In addition, the mixing of PBO with insecticides decreased knockdown resistance coefficients on Ankara housefly populations. Thus, it was found that PBO had important function in preventing the occurrence of knockdown resistance and in increasing the biological effects of insecticides on housefly populations.