DO HYPOTHYROIDISM AND HYPERTHYROIDISM AFFECT RESTLESS LEG SYNDROME, SLEEP AND ITS QUALITY?

Abstract

We aimed to evaluate the frequency of restless legs syndrome (RLS) and its sleep disturbance in patients with thyroid dysfunction. Methods: 31 patients with hypothyroidism and 31 patients with hyperthyroidisim as study groups and 30 age and gender-matched healthy volunteers as a control group were enrolled in the study. The diagnosis of RLS was made according to the criteria of the International RLS Study Group. Extreme daytime sleepiness, sleep quality and insomnia estimated by assessment tools Results: Among our study population, the median age was 41.50 (min-max = 20-72). 4 patients in the hypothyroid group and 7 patients in the hyperthyroid group were female. The RLS-diagnosed patients were significantly higher in the hypothyroid group than the hyperthyroid group. While subjective sleep quality and sleep latency were significantly different in the study population, there was no correlation between all groups in sleep quality according to PSQI. ESS and ISI scores were not significantly different in all groups. When the subsequent categorization of BDI into mild, moderate and severe was made, a significant difference was found between the three groups (p=0.010). Among the study groups although the percentage of low-BDI patients in the control group was higher (70%), the percentage of the severe-BDI was higher in the hyperthyroid group (16.13%). The severity of anxiety scores was not measured significantly between all groups according to the HAS (p=0.486). Conclusion: The frequency of RLS was significantly higher in the hypothyroid group. Those who had more severe depression scores according to the depression assessment scales were higher in the hyperthyroid group.